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Global Gene Therapy in Oncology Market Size & Share Analysis - By Product Type, By Application, By Region - Forecasts (2024 - 2031)


The "Gene Therapy in Oncology Market Research Report" provides an in-depth and up-to-date analysis of the sector, covering key metrics, market dynamics, growth drivers, production elements, and details about the leading Gene Therapy in Oncology manufacturers. The Gene Therapy in Oncology market is projected to expand at a CAGR of 12.1% during the forecast period (2024 - 2031).


Gene Therapy in Oncology Market Sizing and Forecast


Gene Therapy in Oncology involves the use of genetic modification techniques to treat cancer by altering the genetic material within cancer cells or the patient's immune cells to fight tumors more effectively. This innovative approach encompasses several methods, including inserting therapeutic genes, knocking down oncogenes, and harnessing immune responses through engineered T-cells.

The importance of gene therapy within the oncology sector is substantial, as it offers potential cures or long-term remissions for cancers that are resistant to conventional therapies, addressing an increasing need for more effective and personalized treatments.

From 2024 to 2031, the market is projected to experience a notable Compound Annual Growth Rate (CAGR), driven by advancements in technology, increasing clinical trials, and a growing understanding of genetic factors in cancer progression. Significant trends impacting this growth include rising investment in research and development, approval of innovative therapies, and expanding collaborations between biotech firms and academic institutions.

Regionally, North America is expected to hold the largest market share, followed by Europe and the Asia-Pacific, where growing healthcare infrastructure and rising prevalence of cancer are noteworthy considerations. Overall, the Gene Therapy in Oncology market is poised for robust growth with transformative potential in cancer treatment.


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Who are the Major Gene Therapy in Oncology Market Companies?


  • Bristol-Myers Squibb
  • Cold Genesys
  • Advantagene
  • Amgen
  • AstraZeneca
  • Bio-Path Holdings
  • CRISPR Therapeutics
  • Editas Medicine
  • Geron Corp
  • Idera Pharmaceuticals
  • Intellia Therapeutics
  • Johnson & Johnson
  • Marsala Biotech
  • Merck
  • Mologen AG
  • Oncolytics Biotech
  • Oncosec
  • Oncotelic
  • Shenzhen SiBiono GeneTech
  • Sillajen Biotherapeutics
  • Tocagen
  • UniQure
  • Ziopharm Oncology


The gene therapy in oncology market is a rapidly evolving landscape, driven by innovations in targeted therapies and increased investment in research and development. Key players such as Bristol-Myers Squibb, Amgen, and AstraZeneca lead the market with their advanced therapies and strategic acquisitions. Companies like Cold Genesys and Oncolytics Biotech focus on viral vector treatments, pushing the boundaries of immuno-oncology.

Bristol-Myers Squibb remains a stalwart with its leading immunotherapies, exploring gene-modified cell therapies. Amgen is advancing in targeted therapies, while AstraZeneca emphasizes its commitment to combining gene therapy with its robust oncology pipeline. CRISPR Therapeutics and Editas Medicine are at the forefront of gene-editing technologies, offering novel approaches to address genetic mutations in cancers.

Companies like Bio-Path Holdings and Intellia Therapeutics highlight the trend towards personalized medicine with their specific targeting of tumor-associated antigens. Oncosec and Tocagen focus on intratumoral delivery methods, enhancing the local effectiveness of therapies.

Market insights indicate a substantial growth trajectory, with the global gene therapy market expected to surpass $8 billion by 2026. Specific revenue highlights include:

- Bristol-Myers Squibb: Approx. $42 billion in total revenue (2022).

- Amgen: $26 billion in total revenue (2022).

- AstraZeneca: $44 billion in total revenue (2022).

- Merck: $59 billion in total revenue (2022).

Such financial capabilities of these companies contribute significantly to the rapid advancements and commercialization efforts within the gene therapy in oncology sector.


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Market Segmentation by Type


The Gene Therapy in Oncology Market is categorized into:


  • Ex Vivo
  • In Vivo


The Gene Therapy in Oncology market primarily features two types: Ex Vivo and In Vivo. Ex Vivo gene therapy involves modifying a patient's cells outside the body, typically by harvesting them, altering their genetic material, and then reinfusing them to target cancer. In Vivo gene therapy directly delivers therapeutic genes into the patient's body, utilizing viral vectors or other delivery systems to target cancer cells. Both approaches aim to enhance anti-tumor immunity, correct genetic defects, and improve treatment outcomes in cancer patients.


Market Segmentation by Application


The Gene Therapy in Oncology Market is divided by application into:


  • Hospitals
  • Diagnostics Centers
  • Research Institutes


Gene therapy in the oncology market has applications across various sectors, including hospitals, diagnostics centers, and research institutes. In hospitals, gene therapy is utilized for innovative cancer treatments, offering targeted approaches to combat tumors. Diagnostics centers employ gene therapy techniques for personalized medicine, enhancing treatment accuracy. Research institutes focus on developing and testing new gene-based therapies, advancing understanding of cancer biology. Together, these applications aim to improve patient outcomes and drive the evolution of cancer treatment strategies.


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Key Highlights of the Gene Therapy in Oncology Market Research Report:



  • Market Outlook (2024- 2031)

  • Porter’s Five Forces Analysis

  • Market Drivers and Success Factors

  • SWOT Analysis

  • Value Chain

  • Comprehensive Mapping of the Competitive Landscape

  • Industry Outlook & Critical Success Factors (CSFs)

  • Market Segmentation & Value Chain Analysis

  • Industry Dynamics

  • Key Opportunities

  • Application Outlook

  • Technology Outlook

  • Regional Outlook

  • Competitive Landscape

  • Company Market Share Analysis

  • Key Company Profiles


Future of Gene Therapy in Oncology Market - Driving Factors and Hindering Challenges


The Gene Therapy in Oncology market is poised for significant growth, driven by advancements in precision medicine, increased R&D investment, and successful clinical trials. Key entry strategies include collaborations with biotech firms, leveraging AI for patient personalization, and developing combination therapies. Market disruptions may arise from regulatory changes and ethical debates around gene editing. Opportunities lie in targeting rare cancers and utilizing novel delivery systems like viral vectors. Innovative approaches involve addressing manufacturing challenges through automation and enhancing accessibility via partnerships with healthcare providers, ultimately transforming cancer treatment landscapes.


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Geographical Market Analysis


The regional analysis of the Gene Therapy in Oncology Market covers:



North America:


  • United States

  • Canada



Europe:


  • Germany

  • France

  • U.K.

  • Italy

  • Russia



Asia-Pacific:


  • China

  • Japan

  • South Korea

  • India

  • Australia

  • China Taiwan

  • Indonesia

  • Thailand

  • Malaysia



Latin America:


  • Mexico

  • Brazil

  • Argentina Korea

  • Colombia



Middle East & Africa:


  • Turkey

  • Saudi

  • Arabia

  • UAE

  • Korea




The Gene Therapy in Oncology market is witnessing significant growth across various regions, driven by advancements in technology, increasing prevalence of cancer, and supportive regulatory frameworks.

In North America, particularly the United States, the market is expected to dominate due to high investments in research and development, advanced healthcare infrastructure, and a robust pipeline of gene therapy products. The region is projected to hold approximately 45% of the global market share.

Europe, led by Germany, France, and the ., is also experiencing growth, attributed to strong regulatory support and increasing collaboration between public and private sectors. The market share in this region is estimated at around 25%.

The Asia-Pacific region presents substantial growth opportunities, particularly in China and Japan, driven by rising healthcare expenditures, population aging, and increasing awareness of gene therapies. This region's market share is expected to reach about 20%.

Latin America, including Mexico and Brazil, is gradually emerging, with a projected share of 7%, influenced by increasing investments in healthcare innovation.

The Middle East and Africa, particularly countries like Saudi Arabia and the UAE, are at an early stage of market development, anticipating a market share of approximately 3%. Overall, North America is expected to maintain its lead, with global expansion opportunities in emerging markets.


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