Lipid nanoparticles (LNPs) are the most advanced non-viral gene delivery systems in clinical practice. Lipid nanoparticles can overcome a major obstacle in the development and application of genetic drugs, and safely and effectively transport nucleic acids. Gene drugs have many different application fields, such as gene editing, rapid vaccine development, tumor immunotherapy for rare genetic diseases and non-drug-resistant diseases, and so on; All of these application areas are often hindered by low efficiency in nucleic acid delivery. LNP consists of four components: ionized lipid phospholipids, PEG lipids, cholesterol like structures, and lipids. These four components form a sphere with a diameter of about 100 nm, which can encapsulate mRNARNA i gene editing scissors and deliver them into the LNP sphere. The most critical component of LNP is ionized lipids, which are the key components for LNP to escape from its inner body. The new development of medicine has made drugs and their active ingredients increasingly complex and brought new challenges. For example, oligonucleotides are easily degraded in the human body. The latest research suggests that LNPs can form a stable environment for protecting active ingredients such as RNA, mRNA, siRNA, or DNA based APIs. The optimization of nucleic acid drugs and targeted cell delivery pathways is currently a very popular research field. Lipid nanoparticles (LNPs) are commonly used to encapsulate and deliver drugs such as mRNA. The LNP production equipment is used for the preparation and production of these lipid nanoparticles.
Explosive demand for mRNA vaccines: Since the COVID-19 outbreak in 2020, mRNA vaccine technology has gained widespread attention. The production of major vaccines such as Pfizer-BioNTech and Moderna cannot be separated from LNP as a carrier. Therefore, the expansion of the mRNA vaccine market provides huge opportunities for the LNP production equipment market.
Growth of gene therapy: LNP is not only used in vaccines, but also plays a key role in gene therapy. With the maturity of gene therapy technology, especially the development of CRISPR technology, LNP will be more widely used in gene editing, cancer immunotherapy, etc., which provides more market opportunities for new equipment manufacturers.
According to the new market research report “Global Lipid Nanoparticle (LNP) Production Equipment Market Insights, Forecast to 2030”, published by QYResearch, the global Lipid Nanoparticle (LNP) Production Equipment market size is projected to reach USD 0.3 billion by 2030, at a CAGR of 29.9% during the forecast period.
Source: QYResearch, "Global Lipid Nanoparticle (LNP) Production Equipment Market Insights, Forecast to 2030”
Source: QYResearch, "Global Lipid Nanoparticle (LNP) Production Equipment Market Insights, Forecast to 2030”
According to QYResearch Top Players Research Center, the global key manufacturers of Lipid Nanoparticle (LNP) Production Equipment include Cytiva, Knauer, Micro&Nano Biologics, RainSure Scientific, Nanowetech (guangzhou) Instrument, etc. In 2023, the global top five players had a share approximately 98.0% in terms of revenue.
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